Role of stromal CD10 expression in classifying phyllodes tumors
نویسندگان
چکیده
منابع مشابه
Stromal CD10 expression in mammary fibroadenomas and phyllodes tumours.
BACKGROUND/AIMS CD10 (CALLA) has recently been reported to be expressed in spindle cell neoplasia, and has been used to differentiate endometrial stromal sarcoma from leiomyoma and leiomyosarcoma. In the breast, myoepithelial cells express CD10, but there are few studies of the expression of CD10 in mammary fibroepithelial lesions. METHODS Stromal CD10 expression was studied in 181 mammary ph...
متن کاملComparison of stromal CD10 expression in benign, borderline, and malignant phyllodes tumors among Egyptian female patients.
BACKGROUND Phyllodes tumors are group of biphasic fibroepithelial tumors of the breast of varying malignant potential, ranging from benign tumors to fully malignant sarcomas. According to the Egyptian National Cancer Institute, female malignant cases showed appreciable increase in the recent time period for breast cancer with the malignant phyllodes tumors representing 0.41% of cases in the yea...
متن کاملPhyllodes tumors of the breast: the role of pathologic parameters.
We aimed to establish whether morphologic parameters were prognostically important in a large series of breast phyllodes tumors in Asian women. Of 335 phyllodes tumors diagnosed at the Department of Pathology, Singapore General Hospital, Singapore, between January 1992 and December 2002, 250 (74.6%) were benign, 54 (16.1%) borderline, and 31 (9.3%) malignant, based on histologic review of archi...
متن کاملPhyllodes Tumors of the Breast
OBJECTIVE To study all patients with phyllodes tumors of the breast which were diagnosed at King Hussien Medical Center and Prince Rashid Military Hospital between the 1st of may 2002 till January 2009. METHODS A total of 26 patients diagnosed to have phylloedes tumors were retrieved from the hospital records. All cases were analyzed and assessed in two main categories: demographical characte...
متن کاملAbundant expression of immunoreactive endothelin 1 in mammary phyllodes tumor: possible paracrine role of endothelin 1 in the growth of stromal cells in phyllodes tumor.
Immunoreactive endothelin 1 (irET-1) concentrations were measured in extracts prepared from 4 phyllodes tumors and 14 fibroadenomas. irET-1 was detectable in all tissue extracts by specific radioimmunoassay, and the mean concentration of irET-1 was 18-fold and 27-fold higher in tissue extracts from phyllodes tumors than in those from intracanalicular fibroadenomas and pericanalicular fibroadeno...
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ژورنال
عنوان ژورنال: International Journal of Research in Medical Sciences
سال: 2019
ISSN: 2320-6012,2320-6071
DOI: 10.18203/2320-6012.ijrms20193935